7th CAPRI evaluation meeting
EMBL-EBI, Hinxton, UK, April 3-5, 2019
- EMBL-EBI, Hinxton, UK, April 3-5, 2019
- Keynote speakers
- Instruct-ERIC Workshop
- Sponsored by:
- Contact information
Get the latest update on the current status of computational procedures for modeling protein-protein interactions and the association of proteins with other macromolecules from this 7th CAPRI evaluation meeting. For more information - http://www.ebi.ac.uk/msd-srv/capri/
CAPRI (Critical Assessment of Predicted Interactions) is a community wide experiment designed to test methods for predicting the structure of macromolecular complexes based on the known structure of their components.
The meeting program will include an overview of the performance of protein docking and scoring procedures obtained for targets evaluated since the spring of 2013. It will also feature several plenary lectures by prominent scientists, as well as talks by the best CAPRI performers, and/or groups developing innovative computational approaches. CAPRI groups selected for oral representations will be notified, once the predictions for all outstanding targets have been completed.
We hope to see you all in Hinxton in April!
|Madan Babu (MRC Laboratory of Molecular Biology)||Louise Walport (Francis Crick Institute)|
|Todd O. Yeates (University of California, Los Angeles)||Caroline Lynn Kamerlin (Uppsala University)|
|08:30||Coach from Cambridge|
|09:30 - 10:00||Registration|
|10:00 - 10:15||Sameer Velankar (European Bioinformatics Institute)|
|Session 1: CAPRI Targets and Evaluation Results|
|CAPRI Prediction Results|
|10:15 - 11:00||Marc Lensink (University of Lille, France)|
|The CAPRI-CASP Experiment|
|11:00 - 11:45||Shoshana Wodak (Free University of Brussels, Belgium)|
|11:45 - 13:25||Poster session and lunch|
|Session 2: Highlights from CAPRI Prediction Results and Methods I|
|13:25 - 13:50||Selected abstract talk 1|
|13:50 - 14:15||Selected abstract talk 2|
|14:15 - 14:40||Selected abstract talk 3|
|14:40 - 15:05||Selected abstract talk 4|
|15:05 - 15:20||Coffee break|
|Keynote Lecture I – Title TBC|
|15:20 - 16:10||Madan Babu (MRC Laboratory of Molecular Biology)|
|Session 4: Themed session I|
|16:10 - 16:25||Selected abstract talk 5|
|16:25 - 16:40||Selected abstract talk 6|
|16:40 - 16:55||Selected abstract talk 7|
|17:30 – 20:00||Poster Session and Buffet|
|08:30||Coach from Cambridge|
|Keynote Lecture II – Title TBC|
|09:30 - 10:20||Louise Walport (Francis Crick Institute)|
|10:20 - 10:50||Coffee break|
|Session 5: Highlights from CAPRI Prediction Results and Methods II|
|10:50 - 11:05||Selected abstract talk 8|
|11:05 - 11:20||Selected abstract talk 9|
|11:20 - 11:35||Selected abstract talk 10|
|11:35 - 11:50||Selected abstract talk 11|
|11:50 - 14:00||Poster session and lunch|
|Keynote Lecture III – Title TBC|
|14:00 - 14:50||Todd O. Yeates (University of California, Los Angeles)|
|14:40 - 15:05||Coffee break|
|Session 7: Themed Session II|
|15:05 – 15:20||Selected abstract talk 12|
|15:20 - 15:35||Selected abstract talk 13|
|15:35 - 15:50||Selected abstract talk 14|
|15:50 - 16:05||Selected abstract talk 15|
|16:05 - 16:30||Coffee break|
|Session 8: Themed Session III|
|16:30 - 16:45||Selected abstract talk 16|
|16:45 - 17:00||Selected abstract talk 17|
|17:00 - 17:15||Selected abstract talk 18|
|17:15 - 17:30||Selected abstract talk 19|
|Round Table Discussion|
|17:30 - 19:00||Modeling protein assemblies and CAPRI, what next?|
|19:45 - 22:00||Conference dinner. Homerton College|
|08:30||Coach from Cambridge|
|Keynote Lecture IV – Title TBC|
|09:30 - 10:20||TBC|
|10:05 - 10:30||Coffee break|
|Session 9: Themed Session IV|
|10:30 - 10:55||Selected abstract talk 20|
|10:55 - 11:20||Selected abstract talk 21|
|11:20 - 11:45||Selected abstract talk 22|
|11:45 - 13:00||Lunch|
|Keynote Lecture V – Title TBC|
|13:00 - 13:50||TBC|
|Session 10: Themed Session V|
|13:50 - 14:15||Selected abstract talk 23|
|14:15 - 14:40||Selected abstract talk 24|
|14:40 - 15:05||Selected abstract talk 25|
|15:05 - 15:20||Meeting closing remarks|
|15:20 - 15:40||Coffee break|
|15:40||Shuttle to Cambridge|
EMBL-EBI, Hinxton, UK
European Bioinformatics Institue, EMBL-Outstation
Wellcome Trust Genome Campus
Registration for the 7th edition of the CAPRI evaluation meeting in Hinxton is open.
The registration fee for participants is set to £260 which includes:
3 days of scientific sessions including coffee-breaks and lunch on Wednesday, Thursday and Friday
Ongoing access to the poster area
Certificate of attendance
All participants (excluding keynote speakers) are requested to pay the registration fee. Depending on availability of funds, a contribution towards travel and accommodation expenses will be provided to the selected speakers and plenary lecturers. Speakers will be notified by e-mail regarding the reimbursement policy.
Registration fee should be paid no later than 8 March 2019.
Accommodation is not included in the registration fee, but we have listed our recommendations for several hotel options in Cambridge.
Registrations are now closed.
Important guidelines for participants
A one page Abstract should be submitted for both oral and poster presentations. The deadline for Abstract submission is set to March 3 2019. Selected speakers will be notified by March 11 2019. Please email your abstract in Microsoft word format to firstname.lastname@example.org.
Following the tradition of the meeting, the selected speakers will also be invited to contribute to the special issue of Proteins dedicated to CAPRI that will be published late 2019. Participants who apply for a regular talk should thus present work that is publishable and agree to contribute a manuscript for the Proteins special issue.
Accommodation is not provided for this event. Attendees are requested to arrange their own if required. It is strongly advised to book accommodation a month in advance as room prices tend to increase substantially closer to the date.
Staying on-site (Hinxton)
If you wish to stay in Hinxton, we recommend using the onsite accommodation - Wellcome Genome Campus Conference Centre. Book early as space is limited.
Hinxton Hall, Wellcome Genome Campus
Tel: +44(0) 1223 495 000
Fax: +44(0) 1223 495 114
Holiday Inn Express Cambridge
15-17 Coldhams Park, Cambridge
Tel: +44 0871 902 1605
ibis Cambridge Central Station
2 Station Square, Cambridge
Cambridge Leisure Park, Clifton Way, Cambridge
Tel: +44 (0)871 984 6101
Airbnb is a trusted community marketplace for people to list, discover, and book unique accommodation around the world. Visit https://www.airbnb.com for more information.
There will be a free bus service organised to/from the venue in Hinxton to multiple stops in Cambridge. The pick up and drop off points in Cambridge are - Grafton Centre, Cambridge railway station and Mowbray road. Specific details will be sent closer to the date.
Registration now open for the Joint Instruct-ERIC/CAPRI Workshop on Integrated Modelling of Protein-Protein Interactions Workshop. The course will run prior to the 7th CAPRI Assessment Meeting, from the 1st - 2nd April 2019 at EMBL-EBI, Hinxton, UK.
The course will consist of six sessions followed by a practical component overseen by the lecturer and an additional tutor. During the computer practicals, participants will learn to use and apply the various software with either their own data/structures, or with examples provided by the instructors.
Registration is free for participants from Instruct-ERIC countries and £250 from other countries. Visit the website to find out if you are from a participating Instruct-ERIC country. https://instruct-eric.eu/countries
Note: If you are from an Instruct-ERIC country, please select the option ‘I will pay later’ at the payment stage to register for free.
Accommodation is not included in the registration fee.
Day 1 - 1st April 2019
|11:10||Coach from Cambridge Station|
|12:00 - 13:00||Registration and Lunch|
|13:00 - 15:00||Introduction to protein-protein docking: sampling and scoring|
|Practical: Flexible docking with SwarmDock|
|Paul A. Bates, and Raphael A.G. Chaleil, Francis Crick Institute, London, UK|
|15:00 - 15:30||Coffee Break|
|15:30 - 17:30||Integrative structure determination of macromolecular assemblies|
|Practical: Determination of macromolecular structure using Cryo-EM data|
|Maya Topf and Sony Malhotra, Institute of Structural and Molecular Biology, London, UK|
Day 2 - 2nd April 2019
|08:00||Coach from Cambridge|
|09:00 - 11:00||Introduction to data-driven docking|
|Practical: Integrative docking with HADDOCK|
|Alexandre M.J.J. Bonvin and Panos Koukos, Bijvoet Center for Biomolecular Research, Utrecht, NL|
|11:00 - 11:15||Coffee Break|
|11:15 - 13:15||Protein-protein binding affinities|
|Practical: Modelling interaction strength using machine learning|
|Iain H. Moal, EMBL European Bioinformatics Institute, Cambridge, UK|
|13:15 - 14:00||Lunch|
|14:00 - 16:00||Protein structure prediction|
|Practical: Modelling protein structures and variants: Phyre, PhyreRisk, Missense3D and EzMol|
|Michael J.E. Sternberg, Lawrence Kelley and Charles Tochukwu, Imperial College London, London, UK|
|16:00 - 16:15||Coffee Break|
|16:15 - 18:15||The validation and verification of protein structure|
|Practical: Hands-on assessment of structural quality|
|Gerard Kleywegt, EMBL European Bioinformatics Institute, Cambridge, UK|
There will be a free bus service organised to/from the venue in Hinxton to Cambridge Station. Specific details will be sent closer to the date.
Michelle Mendonca - email@example.com - +44 (0) 1223 494335